Unsourced material may be challenged and removed. Per CLP Regulation, outdated per 1 June 2017. Flammability code 1: Must be pre-heated before ignition can occur. Health code 1: Exposure would cause renal function test interpretation pdf but only minor residual injury.
Reactivity code 0: Normally stable, even under fire exposure conditions, and is not reactive with water. If the filtration in the kidney is deficient, creatinine blood levels rise. GFR estimate, in particular in severe renal dysfunction. The conversion is nonenzymatic and irreversible. Men tend to have higher levels of creatinine than women because, in general, they have a greater mass of skeletal muscle. The mechanism by which creatinine kills bacteria is not presently known. Elevated creatinine is not always representative of a true reduction in GFR.
A high reading may be due to increased production of creatinine not due to decreased kidney function, to interference with the assay, or to decreased tubular secretion of creatinine. Intense exercise can increase creatinine by increasing muscle breakdown. Dehydration secondary to an inflammatory process with fever may cause a false increase in creatinine levels not related to an actual kidney injury, as in some cases with cholecystitis. Several medications and chromogens can interfere with the assay. Creatinine secretion by the tubules can be blocked by some medications, again increasing measured creatinine. Measuring serum creatinine is a simple test, and it is the most commonly used indicator of renal function.